Footnotes

• Twitter @AnandVKulkarni2

• Contributors AK prepared the study protocol, cared for the patients, was involved in data analysis and drafting of the manuscript; CSM helped in preparing the study protocol and data collection and cared for patients; BAG collected the data; ST collected the data and cared for the patients; KR involved in patient care; AS involved in patient care; MS helped with initial drafting of the manuscript; SS helped in data collection; DG provided the laboratory support; PNR critically assessed the protocol and manuscript for accuracy; DNR served as scientific advisor and critically assessed the final manuscript. AK and DNR are the guarantors of the study. All members approved the final draft of the manuscript.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests None declared.

• Provenance and peer review Not commissioned; internally peer reviewed.

• Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.