Table 2

Summary of caspase 3/7 activity following treatment with the best drug combination

Cell lineDrug target(s)Time (h)Cleaved caspase 3/7 (% of control for 1 M drug concentration)
OE19ErbB2/EGFR24400
MKN45Met24200
KatoIIIFGFR24200
HSC39ErbB2/EGFR-Met-FGFR24500
OE33ErbB2/EGFR-Met48400