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Hepatology
Original article
Glial cell line-derived neurotrophic factor (GDNF) mediates hepatic stellate cell activation via ALK5/Smad signalling

Authors

  • Le Tao Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China Laboratory of Liver Disease, Department of Infectious Disease, PutuoHospital , Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Wenting Ma Laboratory of Liver Disease, Department of Infectious Disease, PutuoHospital , Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Liu Wu Laboratory of Liver Disease, Department of Infectious Disease, PutuoHospital , Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Mingyi Xu Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Yanqin Yang Department of Pathology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Wei Zhang Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Wenjun Sha Departmentof Endocrinology and Metabolism, PutuoHospital , Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Hongshan Li Department of Hepatology, HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, China PubMed articlesGoogle scholar articles
  • Jianrong Xu Department of Pharmacology and Chemical Biology, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Rilu Feng Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Dongying Xue Laboratory of Liver Disease, Department of Infectious Disease, PutuoHospital , Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Jie Zhang Laboratory of Liver Disease, Department of Infectious Disease, PutuoHospital , Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Steven Dooley Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Ekihiro Seki Division of Digestive and Liver Diseases, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Ping Liu Shanghai University of Traditional Chinese Medicine, Shanghai, China Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Cheng Liu Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China Laboratory of Liver Disease, Department of Infectious Disease, PutuoHospital , Shanghai University of Traditional Chinese Medicine, Shanghai, China Shanghai Putuo Central School of Clinical Medicine, Anhui Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  1. Correspondence to Steven Dooley, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; steven.dooley{at}medma.uni-heidelberg.de, Ekihiro Seki, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA; Ekihiro.Seki{at}cshs.org, Ping Liu, Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; liuliver{at}vip.sina.com and Cheng Liu, Central Laboratory and Laboratory of liver disease, Department of Infectious Disease, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China; liucheng0082010{at}163.com
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Citation

Tao L, Ma W, Wu L, et al
Glial cell line-derived neurotrophic factor (GDNF) mediates hepatic stellate cell activation via ALK5/Smad signalling
Gut 2019;68:2214-2227.

Publication history

  • Received November 5, 2018
  • Revised April 18, 2019
  • Accepted May 3, 2019
  • First published June 6, 2019.
Online issue publication 
November 07, 2019

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.