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Original research
Early detection of colorectal cancer using aberrant circulating cell-free mitochondrial DNA fragmentomics

Authors

  • Siyuan Wang State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Fan Peng State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Miao Dang State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Huanmin Jiao State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Huanqin Zhang State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Kaixiang Zhou State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Wenjie Guo State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Zhiyun Gong Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China PubMed articlesGoogle scholar articles
  • Lin Guo Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China PubMed articlesGoogle scholar articles
  • Renquan Lu Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China PubMed articlesGoogle scholar articles
  • Deliang Li Department of Gatroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China PubMed articlesGoogle scholar articles
  • Bingrong Liu Department of Gatroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China PubMed articlesGoogle scholar articles
  • Xu Guo State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Jinliang Xing State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, Shaanxi, China PubMed articlesGoogle scholar articles
  • Yang Liu Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi'an, China PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Yang Liu; liuyangfmmu{at}163.com; Professor Jinliang Xing; xingjl{at}fmmu.edu.cn
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Citation

Wang S, Peng F, Dang M, et al
Early detection of colorectal cancer using aberrant circulating cell-free mitochondrial DNA fragmentomics
Gut 2025;74:961-970.

Publication history

  • Received August 5, 2024
  • Accepted November 26, 2024
  • First published December 18, 2024.
Online issue publication 
May 07, 2025

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© Author(s) (or their employer(s)) 2025. No commercial re-use. See rights and permissions. Published by BMJ Group.